닫기
닫기

3rd Asian Congress for Alternatives to Animal Experiments

Alternaives to Animal Experiments:From Asia to the World.

14th-16th December 2022/ICC Jeju - The Korea

ABSTRACT SUBMISSION AND REGISTRATION WILL BE OPEN!!

home

2022 3rd ACAAE Program

1st Day (12/14)
Time Hall A Hall B
13:00-13:20 Opening ceremony
13:20-14:10 3D reconstructed tissue models in toxicology: from initial ideal to regulatory acceptance
PL1 Dr. Helena Kandarova (ESTIV president)
Chair: Prof. Kwang-Mahn Kim
14:10-14:20 Coffee Break
14:20-16:00 S1 : 3R Organize by JSAAE
Organizer: Dr. Taro Kobayashi (Ikeda,Japan)
Chair: Guojun Li (Beijing Center for Disease Prevention and Control, China)
Co-Chair: Dr. Guojun Li (BJCDC, China)
S2 : Novel in Vitro test;
Organizer: Prof. Ok-Nam Bae (Hanyang Univ.,Korea)
Chair: Prof. Yong-Joo Park (Kyungsang Univ.,Korea)
Co-Chair: Dr. Masahiro Takeyoshi (CERI, Japan)
14:20-14:45 A unique method to form spheroids with various designs. (Reduction, Replacement) Nobuhiko Kojima (Yokohama City University) Using in Vitro and Machine Learning Approaches to Determine Dioxin-like Potencies Among Birds for Brominated Dioxin Analogues
Dioxin Analogues, Prof. Rui Zhang(Univ. of Jinan, China)
14:45-15:10 Human iPS Cell-Derived Cardiomyocytes-Based Cardiac Safety Assessment of Drugs
Kentaro Ishida (Myoridge Co. Ltd)
Potential threats of nanoplastic accumulation in human
induced pluripotent stem cells, Prof. Ju-Hyun Park (Kangwon
National Univ., Korea)
15:10-15:35 A 3Rs approach to investigate the barrier models: a
3D perfusion tubular Organ on a chip model
Ph.D Lisa Franziska Drews
Development of novel in vitro methods using human iPS cell technology
Yasunari Kanda (National Institute of Health Sciences, Japan)
15:35-16:00 The Fantastic 4: Simcyp Rat, Mouse, Dog, and Monkey Simulators
Dr. Devendra Pade
A robotised 1546 compound screen in a perfused 3D microfluidic angiogenesis assay, Henriette Lanz (MIMETAS BV)
16:00-16:30 Coffee Break
16:30-18:00 S3 : Education session on 3Rs
Organize by JSAAE

Organizer: Prof. Nobuhiko Kojima (Yokohama City Univ., Japan)
Chair: Prof. Nobuhiko Kojima (Yokohama City Univ., Japan)
Co-chair: Prof. Masaharu Akita
S4 : Oral presentation from
selected posters

Organizer: Prof. Ha Ryong Kim (Daegu Catholic Univ., Korea)
Chair: Prof. Ha Ryong Kim (Daegu Catholic Univ., Korea)
Co-chair
Effort against "Challenge Contest" to educate high school students.
Nobuhiko Kojima (Yokohama City University)
Max 9 speakers
(10 min presentation)
Title-TBA
Ichiro Miyoshi (Japanese Association for Laboratory Animal Science)
New technology to reduce the sacrifice of experimental animals while practice anatomy
David Yoo (3DMediVision)
(Tentative) Activities to increase educational
opportunities for 3Rs in Japan
Masaharu Akita (Kamakura Women's University)
18:30-20:30 Welcome dinner
2nd Day (12/15)
Time Hall A Hall B
09:30-10:20 Development of in vitro alternative assay methods for evaluation of chemicals-mediated immunotoxicities considering comprehensive in vivo toxicities
PL2 Prof. Yong Heo (Daegu Catholic Univ., Korea)
Chair: Prof. Kyung-Chul Choi(Chungbuk Univ)
10:20-10:40 Coffee Break
10:40-12:20 S5 : Cosmetics - safety assessment of cosmetics
Organizer: Dr. Susun An (Amore Pacific, Korea)
Chair: Dr. Megumi Sakuma (KOSE Corp, Japan)
co-Chair: Dr. Rong Kuang (Zhejiang Institute for Food and Drug Control)
S6 : Zebrafish as an alternative models for toxicology
Organizer: Dr. WooKeun Kim (KIT, Korea)

Chair: Dr. Hajime Kojima (NIHS, Japan) co-Chair: Prof. Hongtao Jin (Chinese Academy of Medical
Sciences & Peking Union Medical College)
10:40-11:05 Next Generation Risk Assessment to make safety decisions for cosmetic ingredients
Dr. Matthew Dent (Unilever, UK)
Disease modeling of rare neurological disorders in zebrafish,
Prof. Cheol-Hee Kim (Chungnam National Univ., Korea)
11:05-11:30 Next generation Risk Assessment (NGRA) for skin sensitisation
of cosmetic ingredients, Dr. Woo-Hyuck Choi(LG H&H, Korea)
Use of zebrafish embryo assay in safety assessment of nanoparticles, Dr. Wittaya Pimtong (Nanotec, Thailand)
11:30-11:55 Estimation of dermal permeation and systemic exposure of chemicals through the skin with alternative membrane and in silico model
Hiroaki Todo (Josai Univ., Japan)
The use of Zebrafish teratogenicity assay in pharmaceutical companies,
Kanako Mori (Astellas, Japan)
11:55-12:20 Application of in vitro 3D Reconstructed Human Epidermis Models EpiKutis and EpiSkinTM to Predict Skin Irritation Potential on Formulations, Dr. Jing Sang (Zhejiang Institute for Food and Drug Control, China) Application and practice of zebrafish embryonic development and hepatotoxicity model in safety evaluation with mechanism exploration of traditional Chinese medicine and natural products, Dr. Hongtao Jin (Chinese Academy of Medical Sciences & Peking Union Medical College, China)
12:20-14:00 Lunch & Poster session
14:00-14:50 High throughput screening and evaluation of chemical substances by Omics
PL3 Prof. Xiaowei Zhang (Nanjing Univ., China)
Chair: Dr. Tina Qu
14:50-15:20 Coffee Break
15:20-16:55 S7 : Medical device safety evaluation
Organizer: Dr. Jae-Sung Kwon (Yonsei Univ., Korea)

Chair: Prof. Xiaowei Zhang (Nanjing University, China)
Co-Chair: Dr. Atsuko Miyazima (NIHS, Japan)
S8 : Organ-on-a-chipas an alternative model for drug screening
Organizer: Dr.Ki-Suk Kim (KIT, Korea)

Chair: Prof. Sungho Ko (CHA University)
Co-Chair: Prof.Seiichi Ishida (Sojo Univ., Japan)
15:20-15:45 in vitro methods for biocompatibility of medical devices:
achievements for irritation and perspectives for skin sensitisation ,
Dr.Pellevoisin Christian (MatTek, France)
(Tentative) Research and Development of Microphysiological System in Japan supported by the AMED-MPS project
Prof. Seiichi Ishida (Sojo Univ., Japan)
15:45-16:05 Pre-clinical safety testing platform for medical devices
Dr. Rawiwan Maniratanachote (National Science and Technoloogy Development Agency, Thailand)
Manufacturing of in vitro Tissue Model via 3D bioprinting and Tissue-on-chip Technology, Prof. Ting Zhang (Tsinghua University, China)
16:05-16:30 Development and evaluation of alternative methods to skin sensitization tests for medical devices
Atsuko Miyazima (National Institute of Health Sciences, Japan)
Human Mini-Brains for Neurological Disorders, Prof. Hansang Cho (Sung Kyun Kwan University, Korea)
16:30-16:55 Development of alternative test to irritation tests for medical devices
Prof. Jae-Sung Kwon (Yonsei Univ., Korea)
Identification of human blood-brain barrier shuttles for brain drug delivery using organ-on-a-chip technology, Prof. Tea-Eun Park (UNIST, Korea)
16:55-17:10 Coffee Break
17:10-18:00 Human-relevant replacement methods are ready to take the place of animal experiments
PL4 Prof. Mohammad A. Akbarsha (India) Chair: Prof. Dr. Yong Heo (Daegu Catholic Univ., Korea)
18:00-20:00 Banquet
3rd Day (12/16)
Time Hall A Hall B
09:30-10:20 Toward ideal prediction of human responses based on physiological in vitro systems
PL5 : Prof. Yasuyuki Sakai (Univ. Tokyo Japan)
Chair: Dr. Masato Hatao
10:20-10:40 Coffee Break
10:40-12:20 S9 : Animal Free Safety Assessment
Organizer: Ms. Seo, Borami (HSI, Korea)
S10 : Artificial intelligence as an alternative & predictive model
Organizer: Dr. Seokjoo Yoon (KIT, Korea)

Chair: Dr. Wei Shi(Jiangsu Province Ecology and Environment
Protection Key Laboratory of Chemical Safety and Health Risk,
China)
Co-Chair: Dr.Takahashi Yamada (NIHS, Japan)
10:40-11:05 Introduction: AFSA Cosmetics Education and
Training Program
Catherine Willett (HSI)
Consumer Exposure
Ted Xing (L'Oréal )
Artificial intelligence, machine learning and Data Analytics for
Alternatives to Animal Experiments, Dr. Wei Shi(Jiangsu
Province Ecology and Environment Protection Key Laboratory
of Chemical Safety and Health Risk, China)
11:05-11:30 In silico tools and Read-Across
Jin Li (Unilever)
Advanced Machine Learning in Predictive Toxicology:
Explainable AI, Dr. Igor Tetko (Helmholzt institue, Germany)
11:30-11:55 Dosimetry: Internal Exposure
Yuan Gao (Procter and Gamble)
Pushing the boundaries of in silico models beyond
organic molecular structure-centered chemical space,
Dr. Hyun-Kil Shin (KIT, Korea)
11:55-12:20 AFSA Module 9: Global Regulatory Landscape
Dr. Jay Ingram (Delphic HSE)
Development of in silico model for
skin sensitization evaluation using machine learning
Kaori Ambe (Nagoya City University, Japan)
12:20 - Closing ceremony
맨위로